Author Guidelines
Aims & Scope
The mission of Alzheimer's & Dementia: The Journal of the Alzheimer's Association (Alzheimer's & Dementia) is to bridge the knowledge gaps across a wide range of bench-to-bedside investigation. Alzheimer's & Dementia publishes the results of studies in: behavior, biochemistry, genetics, molecular biology, pharmacology, physiology, protein chemistry, neurology, neuropathology, psychiatry, geriatrics, neuropsychology, epidemiology, sociology, health services research, health economics, political science and public policy. Alzheimer's & Dementia emphasizes interdisciplinary investigations and integrative/translational articles related to: etiology, risk factors, early detection, disease modifying interventions, prevention of dementia, and applications of new technologies in health services. The Journal will publish only original contributions in the following forms: comprehensive reviews, research articles, information on clinical trials, short reports, in-depth perspectives/open-peer commentaries, theoretical and/or translational papers that attempt to integrate knowledge across disciplines, history and politics of science/ brief biographies, and abstracts of papers presented at international meetings.
Negative results, particularly clinical trials, are published as short communications.
The ultimate objective is to create a novel forum for: rapid communication of new findings, ideas, or perspectives; disseminating knowledge, across the spectrum of basic to clinical studies, necessary for optimal translation of research findings into practical applications/interventions; integrating knowledge across disciplines; increasing knowledge in diverse disciplines to promote early detection/diagnosis and/or interventions; formulating new theories and/or strategies for the rigorous testing of theories or their predictions; identifying promising new directions of research; and providing the scientific impetus for new initiatives or public policies concerning research on prevention and new models of health services.
Research In Context
Alzheimer’s & Dementia requires a section called “Research in Context”. Authors must provide a summary, similar to an abstract, for inclusion during the online submission process. In the summary of 150 words or less, authors must place their results or findings into context with previous work.
The section has three elements.
The “systematic review” subheading describes the process authors used to search, identify, and evaluate the accumulated knowledge related to their scientific question.
The “interpretation” subheading requires authors to declare what their findings contribute to the entirety of the accumulated knowledge related to the question of interest described in the paper.
The “future directions” subheading challenges authors to state specifically the important scientific question or questions that are necessary to expand, confirm, or refute the author’s findings in future research activities. Authors must be specific in outlining or defining future research directions or crucial questions that yet need to be answered.
Here is an example for the Research in Context section:
Systematic review: The authors reviewed the literature using traditional (e.g., PubMed) sources and meeting abstracts and presentations. While the pathophysiology of ARIA is not yet as widely studied as other aspects of AD biology, there have been several recent publications describing the clinical aspects of ARIA. These relevant citations are appropriately cited.
Interpretation: Our findings led to an integrated hypothesis describing the pathophysiology of ARIA. This hypothesis is consistent with nonclinical and clinical findings currently in the public domain.
Future directions: The manuscript proposes a framework for the generation of new hypotheses and the conduct of additional studies. Examples include further understanding: (a) the role of perivascular clearance pathways on vascular changes following anti-Aß immunotherapy; (b) the role of alterations in water clearance mechanisms in the resolution of ARIA; (c) the potential reversibility of microhemorrhage events in the clinical setting; and (d) the relationship between the pathophysiology of ARIA-E and ARIA-H.
Please see the editorial on page 171 in the May 2012 issue for further details.
Note: The Research in Context should be uploaded as a "Supporting File" when submitting the manuscript files via Editorial Manager.
Article Types
Review Articles:
Comprehensive Reviews are commissioned papers by the editors to provide comprehensive and balanced coverage of a timely and/or controversial issue by a recognized authority. Uninvited paper will not be reviewed. The invited review should integrating different points of view on ground-breaking, fast-moving or contentious topics with the objective of translating, informing or educating a wide multi-disciplinary audience about varying perspective. Reviews should provide a brief overview or background of critical issues and then concentrate on setting recent findings in context. It is crucial for all Reviews, particularly those tackling controversial topics, to provide a well-balanced view of developments; authors must never concentrate unduly on their own research. Reviews, unlike Research Articles , do allow some speculation designed to foster the formulation or testing of new hypothesis.
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https://alz-journals.onlinelibrary.wiley.com/hub/journal/15525279/homepage/author-guidelines
