Postdoctoral fellow position in immunology at the UT Southwestern Medical Center
A postdoctoral fellow position is open in the laboratory of Dr. Tuoqi Wu in the Department of Immunology and the Harold C. Simmons Comprehensive Cancer Center at the UT Southwestern Medical Center (https://profiles.utsouthwestern.edu/profile/208407/tuoqi-wu.html) The Wu laboratory aims to understand the molecular programs governing T cell stemness and exhaustion during cancer and chronic viral infection and to identify targets to improve the antitumor T cell response during immunotherapies. In addition, the Wu lab is interested in understanding how aging impairs immunity during tumorigenesis and infection. Studies will utilize cutting-edge next-generation sequencing, CRISPR-Cas9 knockout screen, bioinformatics as well as molecular and cellular immunology approaches.
Dr. Wu received his PhD degree from Emory University. He performed his postdoctoral research at the National Institutes of Health (NIH). Dr. Wu is currently an assistant professor in the Department of Immunology at the UT Southwestern Medical Center. He has received multiple prestigious awards including an ASPIRE Award for Outstanding Early Career Investigators (The American Association of Immunologists), a V Scholar Award, a Cancer Research Institute Clinic & Laboratory Integration Program Award, an American Federation for Aging Research Junior Faculty Grant and a Norman P. Salzman Memorial Award in Virology. His research is supported by the NIH, Cancer Research Institute, V foundation, American Federation for Aging Research and generous startup fund from UT Southwestern.
Relevant publications:
1.Yao C*, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D’Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O’Shea JJ, Schwartzberg PL, Wu T*. BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8 T cells. Nature Immunology, 2021 Mar;22(3):370-380. PMID: 33574619 *corresponding authors.
2.Yao C, Sun HW, Lacey NE, Ji Y, Moseman EA, Shih HY, Heuston EF, Kirby M, Anderson S, Chen J, Khan O, Handon R, Reilley J, Fioravanti J, Hu J, Gossa S, Wherry EJ, Gattinoni L, McGavern DB, O'Shea JJ*, Schwartzberg PL*, Wu T*. Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection. Nature Immunology, 2019 Jul;20(7):890-901. PMID: 31209400 *corresponding author
3.Wu T*, Ji Y, E. Moseman EA, Manglani M, Kirby M, Anderson S, Handon R, Kenyon E, Elkahloun A, Wu W, Gattinoni L, McGavern DB, Schwartzberg PL*. The TCF1-Bcl6 axis counteracts type I interferon to repress T cell exhaustion and maintain T cell stemness in chronic viral infection. Science Immunology, 2016 Dec 23;1(6):eaai8593. PMID: 28018990 *corresponding authors.
Complete List of Papers:
https://www.ncbi.nlm.nih.gov/myncbi/1dq6nbpme5ZMHQ/bibliography/public/
Requirements:
·PhD degree in immunology, microbiology, cancer biology, neuroscience or relevant fields
·Experience with molecular biology
·Comfortable working with mice and/or patient samples
Candidates who meet the above criteria are welcome to send their CV, cover letter, and contact information of references to Dr. Tuoqi Wu at tuoqi.wu@utsouthwestern.edu.
转自：“iNature”微信公众号
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