Instructions to Authors
The American Journal of Hypertension is a monthly, peer-reviewed journal that provides a forum for scientific inquiry of the highest standards in the field of hypertension and related cardiovascular disease. The journal publishes high-quality original research and review articles on basic sciences, molecular biology, clinical and experimental hypertension, cardiology, epidemiology, pediatric hypertension, endocrinology, neurophysiology, and nephrology.
Please refer below to the New Publication Model section for additional information about our new online publication policy.
New Publication Model
Preparation of Manuscripts
Format of Manuscripts
Guidelines for Figures and Artwork
Journal Style
Data Availability Policy
Supplementary Information
Submission and Publication
Statistical Guidelines
Contact Information
Open Access & Self Archiving
New Publication Model
Advance Articles are published online before they appear in a regular issue of the Journal. Beginning in August of 2017, articles will first be published as PDFs of the original peer-reviewed author files in order to facilitate rapid access to new content. (Note that this does not apply to editorials or errata.) These files will not be copyedited or typeset. They will contain the watermark “Accepted Manuscript.”
Once an article has been edited, typeset, and finalized, the new version will replace the previous version on the Advance Articles page. Articles will be removed from the Advance Articles page once the issue in which they are published has been posted online.
Accepted manuscripts will be posted online only after the license to publish has been signed; failure to sign the license will result in a delay in online publication.
Preparation of Manuscripts
Content Types
Original Contributions
Original Contributions are manuscripts containing substantial novel research.
Word Limit: 3,000 words maximum excluding abstract, references, tables, and figures
Abstract: 250 words maximum
References: 40 maximum
Figures/Tables: 4 figures, 4 tables maximum
Brief Communications
Brief Communications are manuscripts containing concise and timely information.
Word Limit: 2,000 words maximum, excluding abstract, references, tables, and figures
Abstract: 250 words maximum
References: 20 maximum
Figures/Tables: 1 maximum
Review [generally by invitation of Editors]
Review articles are comprehensive analyses of specific topics in hypertension that are usually solicited by the Editors. Proposals for State of the Art Review articles may be submitted; however, in this case authors should only send an outline of the proposed paper for initial consideration. Both solicited and unsolicited review articles will undergo peer review prior to acceptance. Systematic reviews and meta-analyses should be submitted and treated as Original Contributions.
Word Limit: 4,000 words maximum, excluding abstract, references, tables, and figures
Abstract: 250 words maximum
References: 100 maximum
Figures/Tables: no maximum
Case Reports
Case Reports are manuscripts containing a substantial novel finding.
Word Limit: 1,500 words maximum excluding, references, tables, and figures
Abstract: no abstract for this manuscript type
References: 20 maximum
Figures/Tables: 3 maximum
Hypertension Rounds
Hypertension Rounds are manuscripts containing a substantial novel finding, but with opinions and discussion by some of the authors on the potential approaches in the case that is presented. This would be as if the case was being discussed in Medical Rounds.
Word Limit: 1,500 words maximum excluding references, tables, and figures
Abstract: no abstract for this manuscript type
References: 20 maximum
Figures/Tables: 3 maximum
Commentaries [only by invitation of Editors]
Commentaries typically provide additional insight to the readers based upon the reviewer's perspective of the paper and of the field in general.
Word Limit: 1500 words excluding references, tables, and figures
Abstract: none required
References: 20 maximum
Figures/Tables: 1 maximum
Opinion [generally by invitation of Editors]
Opinion pieces typically provide insight to the readers about specific topics in hypertension and of the field in general. Both solicited and unsolicited manuscripts will undergo peer review prior to acceptance.
Word Limit: 1000 words excluding references, tables, and figures
Abstract: none required
References: 5 maximum
Figures/Tables: 1 maximum
Editorial [only by invitation of Editors]
Editorials typically address broad topics and present a point of view.
Word Limit: 800-1,600 words excluding references, tables, and figures
Abstract: no abstract for this article type
References: 10 maximum
Figures/Tables: 1 maximum
Letters to the Editor
Letters to the Editor typically should address issues concerning recently published information in American Journal of Hypertension and should be received within 6 weeks of the publication of the paper it addresses. A Letter to the Editor must reference the original source, and a Response to a Letter must reference the Letter to the Editor in the first few paragraphs. Letters to the Editor can use an arbitrary title, but a Response must cite the title of the Letter: e.g. Response to [title of Letter].
Word Limit: 500 words excluding references, tables, and figures
Abstract: no abstract for this manuscript type
References: 4 maximum
Figures/Tables: 1 maximum
Book Reviews [only by invitation of Editors]
Review of current relevant published books.
Word Limit: 700 words maximum, excluding references
Abstract: no abstract for this article type
References: N/A
Figures/Tables: 1 maximum
Format of Manuscripts
General format : Manuscripts, including abstracts and references, must be typed in English and double-spaced. All manuscript pages must be numbered. (See Journal Style.)
Title page: This should include
the complete manuscript title of no more than 150 characters;
the running head of no more than 50 characters;
word counts for your abstract and text (the text word count does not include the abstract, references, tables, and figures) in the upper right corner of the title page;
the number of references and the number of figures and tables below the word counts;
all authors' names (listed as first and middle initials followed by last name) and affiliations;
the name, address, telephone, and fax numbers and email address of the corresponding author;
a conflict of interest statement (see DISCLOSURE); and
keywords.
Text : For contributions requiring abstracts, the lengths are defined in the respective sections of Preparation of Manuscripts. Abstracts for Brief Communications and Original Contributions require the headings BACKGROUND, METHODS, RESULTS, AND CONCLUSIONS. For contributions that do not require an abstract, introductory paragraphs may contain references to cited work. Manuscripts should nominally be organized under the following main headings: Introduction, Methods, Results, Discussion, and Disclosure.
Originality : A submitted manuscript must be an original contribution not previously published (except as an abstract), must not be under consideration for publication elsewhere, and, if accepted, must not be reproduced elsewhere without the consent of the American Journal of Hypertension, Ltd. Although the editors, editorial board, and referees make every effort to ensure the validity of published manuscripts, the final responsibility rests with the authors, not with American Journal of Hypertension, its editors, the American Journal of Hypertension, Ltd. or Oxford University Press.
Informed consent and ethics : When reporting experiments on human subjects, indicate whether the procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) or with the Helsinki Declaration of 1975 (as revised in 1983). Include Institutional Review Board or Animal Care and Use Committee approvals.
Clinical Trials Registry : Registration in a public trials registry is required for publication in American Journal of Hypertension. A clinical trial is defined as any research project that prospectively assigns human subjects to intervention or comparison groups to study the cause-and-effect relationship between a medical intervention and a health outcome. Studies designed for other purposes, including exploring pharmacokinetics or safety and tolerability (e.g., phase 1 trials) are exempt.
Registration must be with a registry that meets the following criteria: (1) accessible to the public at no charge; (2) searchable by electronic methods; (3) open to all prospective registrants free of charge or at minimal cost; (4) validates registered information; (5) identifies trials with a unique number; and (6) includes information on the investigator(s), research question or hypothesis, methodology, intervention and comparisons, eligibility criteria, primary and secondary outcomes measured, date of registration, anticipated or actual start date, anticipated or actual date of last follow-up, target number of subjects, status (anticipated, ongoing, or closed), and funding source(s).
Examples of registries that meet these criteria include (1) The registry sponsored by the United States National Library of Medicine; (2) The International Standard Randomised Controlled Trial Number Registry; and (3) European Clinical Trials Database.
Abbreviations: Abbreviations should be defined at the first mention in the text and in each table and figure. For a list of standard abbreviations, please consult the Council of Biology Editors Style Guide (available from the Council of Science Editors, 9650 Rockville Pike, Bethesda, MD 20814) or other standard sources. Write out the full term for each abbreviation at its first use unless it is a standard unit of measure.
Style: The American Medical Association Manual of Style (9th edition), Stedman's Medical Dictionary (28th edition) and Merriam Webster's Collegiate Dictionary (11th edition) should be used as standard references. Refer to drugs and therapeutic agents by their accepted generic or chemical name, and do not abbreviate them (a proprietary name may be given only with the first use of the generic name). Code names should be used only when a generic name is not yet available (the chemical name and a figure giving the chemical structure of the drug are required). Copyright or trade names of drugs should be capitalized and placed in parentheses after the name of the drug. Names and locations (city and state in United States; city and country outside United States) of manufacturers of drugs, supplies, or equipment cited in a manuscript are required to comply with trademark law and should be provided in parentheses. Quantitative data may be reported in the units used in the original measurement (e.g., mg/dl for serum glucose, calcium, phosphorus, creatinine, BUN). SI units are preferred for body weight, mass (weight), volume, and temperature.
Disclosure: All authors are responsible for recognizing and disclosing any conflict of interest that could be perceived to bias their work, making known all financial support and any other personal connections. This includes, but is not limited to: funding, such as salaries, equipment, supplies, reimbursement for attending symposia, etc, from organizations that may gain or lose financially through the publication of the paper; personal financial interests, such as stocks and shares in companies that may gain or lose financially from publication, consultation fees or forms of remuneration from organizations that may gain or lose financially, or patent and patent applications whose value may be affected; and employment, whether recent, present, or anticipated, by an organization that may gain or lose from publication of the paper. Such relationships will be reviewed, and further clarification may be requested if deemed necessary by the editors or reviewers. This information should be included in the title page and in the article under the heading "Disclosure." This section should appear at the end of the main text, before the references. If you have no conflict of interest to declare, please state so in the "Disclosure" section.
Acknowledgments: This should include sources of support, including federal and industry support.
References: References should be typed double-spaced. References are to be numbered in the order of citation within the article. Citations in the main text should appear as superscript Arabic numerals. All authors must be listed. Abstracts must be identified as such. Periodical abbreviations should follow those used by Index Medicus. Personal communications and unpublished data should be included within the text of the manuscript, not as references. Individual references should be formatted in Vancouver style as follows:Journal articles: Lender D, Arauz-Pacheco C, Breen L, Mora-Mora P, Ramirez LC, Raskin P. A double-blind comparison of the effects of amlodipine and enalapril on insulin sensitivity in hypertensive patients. Am J Hypertens 1999; 12:298-303.
Books: Cheriyan J, McEniery C, Wilkinson IB. Hypertension. Oxford University Press, New York, 2010, pp 39-41.
Articles in books: Landzberg M: Clinical assessment of the patient with suspected PAH and the role of cardiac catherization. In Gatzoulis M (ed), Pulmonary Arterial Hypertension. New York, Oxford University Press, 2012, pp. 357-359.
Accessing databases according to AMA:
“In citing data from an online database, include the following elements, if applicable, in the order shown:
Author(s). Title of the database [database online]. Publisher’s location (city, state, or, for Canada, city, province, country, or, all others, city, country): publisher’s name; year of publication and/or last update. URL [provide URL and verify that the link still works as close as possible to publication]. Accessed [date].
Additional notes that might be helpful or of interest to the reader (eg, date the site was updated or modified) may also be included.
PDQ: NCI’s Comprehensive Cancer Database. Bethesda, MD: National Cancer Institute; 1996. http://www.cancer.gov/cancerinfo/pdq/cancerdatabase. Updated December 18, 2001. Accessed April 29, 2004.
Genew, HUGO Gene Nomenclature Committee (HGNC). Human Gene Nomenclature Database Search Engine. http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/searchgenes.pl. Accessed February 27, 2004.
Online Mendelian Inheritance in Man, OMIM. Baltimore, MD: Johns Hopkins University Press; 2000. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM. Accessed December 6, 2005.”
Unpublished data citation according to AMA:
i. “Material Accepted for Publication but Not Yet Published.
Formats suggested for both journal articles and books, accepted for publication but not yet published, are shown below:
Examples:
Carrau RL, Khidr A, Crawley JA, Hillson EM, Davis JK, Pashos CL. The impact of laryngopharyngeal reflux on patient-reported quality of life. Laryngoscope. In press.
Ofri D. Incidental Findings: Lessons From My Patients in the Art of Medicine. Boston, MA: Beacon Press. In press."
When submitting an invited Commentary or Editorial and citing an unpublished article that will appear in the same issue, authors should make a note in the manuscript during submission and/or proof corrections that the reference will be in the current issue. This will alert Production to update the publication details for that reference.
"Material Submitted for Publication but Not Yet Accepted.
In the list of references, do not include material that has been submitted for publication but has not yet been accepted. This material, with its date, should be noted in the text as “unpublished data,” as follows:
Examples:
These findings have recently been corroborated (H. E. Marman, MD, unpublished data, January 2005).
Similar findings have been noted by Roberts6 and H. E. Marman, MD (unpublished data, 2005).
Numerous studies12-20 (also H. E. Marman, MD, unpublished data, 2005) have described similar findings.”
Tables
Each table should be double-spaced on a separate sheet and numbered consecutively in the order of first citation in the text. Minimize empty space. Supply a brief title of no more than 15 words for each, but place explanatory matter in the footnotes (not in the heading). Do not use internal horizontal and vertical lines. Tables should be supplied in separate “table” files in Editorial Manager.
Figures
Figures should be labeled sequentially, numbered, and cited in the text. If a table, figure, or any other previously published material is included, the authors must obtain written permission to reproduce the material in both print and electronic formats from the copyright owner and submit it with the manuscript. The original source should be cited. Figure legends: Legends should be brief and specific, and should appear on a separate manuscript page after the Reference section. All abbreviations used in an illustration should be expanded in the legend.
Additional clarification on tables and figures.
Language Editing:
Language editing, if your first language is not English, to ensure that the academic content of your paper is fully understood by journal editors and reviewers is optional. Language editing does not guarantee that your manuscript will be accepted for publication. Further information on this service. Several specialist language editing companies offer similar services and you can also use any of these. Authors are liable for all costs associated with such services.
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